Mouse Sialic Acid Binding Ig Like Lectin 3 (SIGLEC3) Protein

221€ (10 µg)
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935106861
info@markelab.com
name
Mouse Sialic Acid Binding Ig Like Lectin 3 (SIGLEC3) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx167216
tested applications
WB, SDS-PAGE
Description
Sialic Acid Binding Ig Like Lectin 3 Protein is a recombinant Mouse protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Proteins and Peptides |
Immunogen Target | Sialic Acid Binding Ig Like Lectin 3 (SIGLEC3) |
Host | E. coli |
Origin | Mouse |
Conjugation | Unconjugated |
Observed MW | Molecular Weight: Calculated MW: 28.3 kDa Observed MW (SDS-PAGE): 28 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Asp18-Glu240 Tag: N-terminal His tag |
Expression | Recombinant |
Purity | > 97% |
Size 1 | 10 µg |
Size 2 | 50 µg |
Size 3 | 100 µg |
Size 4 | 200 µg |
Size 5 | 500 µg |
Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
Tested Applications | WB, SDS-PAGE |
Buffer | Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300. |
Availability | Shipped within 5-7 working days. |
Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
Alias | p67,SIGLEC3,SIGLEC-3,CD33rSiglec,Sialic acid-binding Ig-like lectin 3,Myeloid cell surface antigen CD33 |
Background | Protein CD33 |
Status | RUO |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
CD33, also known as Siglec-3 (Sialic acid-binding Ig-like lectin 3), is a transmembrane receptor expressed primarily on cells of myeloid lineage. It belongs to the immunoglobulin (Ig) superfamily and plays a significant role in the regulation of innate immunity. CD33 was first identified in the late 1980s as a marker on acute myeloid leukemia (AML) cells, making it a focal point for research in hematological malignancies. This glycoprotein is encoded by the CD33 gene located on chromosome 19q13.3. CD33 is involved in cellular signaling processes that modulate immune cell function and survival.
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