Mouse Serine/threonine-Protein Kinase Receptor R3 (ACVL1) Protein
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935106861
info@markelab.com
Precio
137.5€ (10 µg)
Protein ACVRL1
proveedor
Abbexareference
abx691227Tested Applications
SDS-PAGEreactivity
status
RUOclonality
Descripción
Mouse Activin Receptor-like Kinase 1 Protein is a recombinant protein from Mouse produced in Human Cells. Recombinant Mouse Activin Receptor-like Kinase 1 is produced by our Mammalian expression system and the target gene encoding Asp23-Pro119 is expressed with a Fc tag at the C-terminus.
Background
ACVRL1, also known as ALK1, is a type I receptor that primarily binds BMP9 and BMP10. It is critical for vascular development and endothelial cell function. ACVRL1 regulates angiogenesis through the SMAD1/5/8 signaling pathway, promoting endothelial proliferation and vessel stability. Mutations in ACVRL1 cause hereditary hemorrhagic telangiectasia (HHT), a genetic disorder characterized by abnormal blood vessel formation and recurrent bleeding. It is primarily expressed in vascular endothelial cells.
Características del producto
category
Proteins and Peptides
origin
Mouse
host
Human
immunogen target
Activin Receptor-like Kinase 1
host
Human
form
Lyophilized
tested applications
SDS-PAGE
size 1
10 µg
size 2
50 µg
expression
Recombinant
purity
> 95% (SDS-PAGE)
buffer
PBS, pH 7.4.
storage
Store at < -20°C.
or code
ACVRL1
dry ice
No
availability
Shipped within 5-15 working days.
alias
Activin receptor-like kinase 1,ALK-1,SKR3
uniprot id
note
This product is for research use only. <p></p> Not for human consumption, cosmetic, therapeutic or diagnostic use.
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