Mouse Serine/threonine-Protein Kinase Receptor R3 (ACVL1) Protein
169€ (10 µg)
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935106861
info@markelab.com
name
Mouse Serine/threonine-Protein Kinase Receptor R3 (ACVL1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx691227
tested applications
SDS-PAGE
Description
Mouse Activin Receptor-like Kinase 1 Protein is a recombinant protein from Mouse produced in Human Cells. Recombinant Mouse Activin Receptor-like Kinase 1 is produced by our Mammalian expression system and the target gene encoding Asp23-Pro119 is expressed with a Fc tag at the C-terminus.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Activin Receptor-like Kinase 1 |
| Host | Human |
| Origin | Mouse |
| Observed MW | Molecular Weight: 38.1 kDa Sequence Fragment: Asp23-Pro119 Tag: C-terminal Fc tag |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Store at < -20°C. |
| Dry Ice | No |
| UniProt ID | Q61288 |
| Alias | Activin receptor-like kinase 1,ALK-1,SKR3 |
| Background | Protein ACVRL1 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
ACVRL1, also known as ALK1, is a type I receptor that primarily binds BMP9 and BMP10. It is critical for vascular development and endothelial cell function. ACVRL1 regulates angiogenesis through the SMAD1/5/8 signaling pathway, promoting endothelial proliferation and vessel stability. Mutations in ACVRL1 cause hereditary hemorrhagic telangiectasia (HHT), a genetic disorder characterized by abnormal blood vessel formation and recurrent bleeding. It is primarily expressed in vascular endothelial cells.
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