Mouse Semaphorin 3E (SEMA3E) Protein

Este producto es parte de SEMA3 - semaphorin 3
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221€ (10 µg)

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935106861
info@markelab.com
name
Mouse Semaphorin 3E (SEMA3E) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx069024
tested applications
WB, SDS-PAGE

Description

Recombinant Semaphorin 3E (SEMA3E) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
Semaphorin 3E (SEMA3E)
Host
E. coli
Origin
Mouse
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 11.9 kDa
Observed MW (SDS-PAGE): 14 kDa
Concentration: Prior to lyophilization: 1200 µg/ml
Sequence Fragment: Ala581-Thr669
Tag: N-terminal His tag
Expression
Recombinant
Purity
> 95%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 10 mM PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in 10 mM PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 5% Trehalose.
Availability
Shipped within 5-12 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P70275
Alias
coll-2,Sema-Z2,Semaphorin-3D
Background
Protein SEMA3E
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

SEMA3E (Semaphorin 3E) stands out for its dual roles in cellular attraction and repulsion, depending on the receptor context. It binds to plexin D1 as its primary receptor, modulating endothelial cell migration, angiogenesis, and neuronal pathfinding. SEMA3E is unique in its receptor-independent signaling pathways, contributing to its versatile biological functions. In cancer, SEMA3E often exhibits a pro-metastatic role, facilitating tumor cell invasion and vascular remodeling. Its aberrant expression is implicated in aggressive tumor phenotypes, making it a target of interest for anticancer therapies aimed at modulating its signaling pathways.

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