Mouse Semaphorin 3E (SEMA3E) Protein
221€ (10 µg)
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935106861
info@markelab.com
name
Mouse Semaphorin 3E (SEMA3E) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx069024
tested applications
WB, SDS-PAGE
Description
Recombinant Semaphorin 3E (SEMA3E) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Semaphorin 3E (SEMA3E) |
| Host | E. coli |
| Origin | Mouse |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 11.9 kDa Observed MW (SDS-PAGE): 14 kDa Concentration: Prior to lyophilization: 1200 µg/ml Sequence Fragment: Ala581-Thr669 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 10 mM PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in 10 mM PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 5% Trehalose. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P70275 |
| Alias | coll-2,Sema-Z2,Semaphorin-3D |
| Background | Protein SEMA3E |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
SEMA3E (Semaphorin 3E) stands out for its dual roles in cellular attraction and repulsion, depending on the receptor context. It binds to plexin D1 as its primary receptor, modulating endothelial cell migration, angiogenesis, and neuronal pathfinding. SEMA3E is unique in its receptor-independent signaling pathways, contributing to its versatile biological functions. In cancer, SEMA3E often exhibits a pro-metastatic role, facilitating tumor cell invasion and vascular remodeling. Its aberrant expression is implicated in aggressive tumor phenotypes, making it a target of interest for anticancer therapies aimed at modulating its signaling pathways.
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