Mouse Roundabout homolog 3 (ROBO3) ELISA Kit

Este producto es parte de ROBO - roundabout guidance receptor
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715€ (96 tests)

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935106861
info@markelab.com
name
Mouse Roundabout homolog 3 (ROBO3) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx543231
tested applications
ELISA

Description

Mouse Roundabout Homolog 3 (ROBO3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Roundabout Homolog 3 concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryELISA Kits
Immunogen TargetRoundabout Homolog 3 (ROBO3)
ReactivityMouse
Detection MethodColorimetric
Assay DataQuantitative
Test Range0.156 ng/ml - 10 ng/ml
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
Size 196 tests
FormLyophilized
Tested ApplicationsELISA
Sample TypeTissue homogenates, cell lysates and other biological fluids.
AvailabilityShipped within 5-15 working days. The validity for this kit is 6 months.
StorageShipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry IceNo
UniProt IDQ9Z2I4
Gene ID19649
AliasHGPS,RIG1,HGPPS,RBIG1,HGPPS1,Roundabout-like protein 3,Roundabout homolog 3
BackgroundElisa kits for ROBO3
StatusRUO
NoteValidity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

ROBO3 (Roundabout Guidance Receptor 3) is a unique member of the Roundabout receptor family with critical roles in axon guidance and neural development. Unlike other ROBO proteins, ROBO3 facilitates the crossing of axons at the midline of the central nervous system by antagonizing Slit-mediated repulsion, a process essential for the development of bilateral neural circuits. ROBO3 expression is tightly regulated during neural development, and mutations in the ROBO3 gene have been linked to horizontal gaze palsy with progressive scoliosis, a rare congenital disorder affecting motor control and spinal development. This receptor’s ability to modulate axon guidance makes it indispensable for proper neural wiring and functional brain organization.

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