Mouse Retinal-Specific ATP-Binding Cassette Transporter (ABCA4) ELISA Kit

Este producto es parte de ABCA4 - Retinal-Specific ATP-Binding Cassette Transporter
Mouse Retinal-Specific ATP-Binding Cassette Transporter (ABCA4) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for ABCA4

proveedor

Abbexa

reference

abx388637

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse Retinal-Specific ATP-Binding Cassette Transporter (ABCA4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Retinal-Specific ATP-Binding Cassette Transporter (ABCA4) concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

ABCA4, also known as the photoreceptor-specific ABC transporter, is expressed in retinal photoreceptor cells, where it facilitates the transport of all-trans-retinal derivatives across photoreceptor disc membranes. This activity is vital for the visual cycle, as it prevents the accumulation of toxic retinoid byproducts that can damage photoreceptors. ABCA4 mutations are linked to several retinal degenerative diseases, including Stargardt disease, cone-rod dystrophy, and retinitis pigmentosa. Structurally, ABCA4 contains two transmembrane and two nucleotide-binding domains, characteristic of ABC transporters, which utilize ATP hydrolysis for substrate translocation. The proper function of ABCA4 is critical for maintaining retinal health and visual function, making it a target for therapeutic interventions in retinal disorders.

Características del producto

category

ELISA Kits


immunogen target

Retinal-Specific ATP-Binding Cassette Transporter (ABCA4)


reactivity

Mouse


test range

78 pg/ml - 5000 pg/ml


sensitivity

< 28 pg/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

ABC10,ABCR,ARMD2,CORD3,FFM,STGD1,ATP binding cassette subfamily A member 4


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

ABCA4


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


Quizá le pueda interesar

anti- ABCA4 antibody

anti- ABCA4 antibody

proveedor

FineTest

reference

FNab09922

Tested Applications

ELISA, WB, IF

reactivity

human,mouse,rat

status

RUO

clonality

polyclonal

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transp...

Precio a consultar

Ver más

anti- ABCA4 antibody

anti- ABCA4 antibody

proveedor

FineTest

reference

FNab10057

Tested Applications

ELISA, IHC

reactivity

human

status

RUO

clonality

polyclonal

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transp...

Precio a consultar

Ver más

Retinal-Specific ATP-Binding Cassette Transporter (ABCA4) Antibody

Retinal-Specific ATP-Binding Cassette Transporter (ABCA4) Antibody

proveedor

Abbexa

reference

abx125474

Tested Applications

ELISA, WB

reactivity

Human, Mouse, Rat

status

RUO

clonality

Polyclonal

ABCA4 Antibody is a Rabbit Polyclonal against ABCA4.

195€ (20 µl)

Ver más