Mouse Receptor-type tyrosine-protein phosphatase zeta (PTPRZ1) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits PTPRZ1
proveedor
Abbexareference
abx540220Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Receptor-type tyrosine-protein phosphatase zeta (PTPRZ1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Receptor-type tyrosine-protein phosphatase zeta concentrations in serum, plasma, tissue homogenates, cell lysates and other biological fluids.
Background
PTPRZ1, also known as RPTPζ, is a receptor-type protein tyrosine phosphatase highly expressed in the central nervous system, particularly in glial cells and neurons. Structurally, PTPRZ1 consists of extracellular carbonic anhydrase-like and fibronectin type III domains, a single transmembrane domain, and two intracellular phosphatase domains. PTPRZ1 regulates cell proliferation, differentiation, and migration, particularly in the context of neural development and repair. It acts as a receptor for pleiotrophin and midkine, growth factors involved in neuroprotection and neural plasticity. PTPRZ1 is crucial for maintaining oligodendrocyte function and myelination in the CNS. Dysregulation or overexpression of PTPRZ1 is associated with glioblastomas, where it promotes cell migration and survival. It is also implicated in neuropsychiatric conditions such as schizophrenia due to its role in synaptic regulation and plasticity. PTPRZ1’s multifunctionality underscores its significance in neural development, repair, and tumor biology.
Características del producto
category
ELISA Kits
immunogen target
Receptor-type tyrosine-protein phosphatase zeta (PTPRZ1)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
detection method
Colorimetric
sample type
Serum,Plasma,Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
PTPZ,HPTPZ,PTP18,PTPRZ,RPTPB,HPTPzeta,PTP-ZETA,RPTPbeta,phosphacan,R-PTP-zeta-2,Protein-tyrosine phosphatase receptor type Z polypeptide 1,Protein-tyrosine phosphatase receptor type Z polypeptide 2,Receptor-type tyrosine-protein phosphatase zeta
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
PTPRZ1
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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