Mouse Receptor-Type Tyrosine-Protein Phosphatase Epsilon (PTPRE) ELISA Kit
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Description
Mouse Receptor-Type Tyrosine-Protein Phosphatase Epsilon (PTPRE) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Receptor-Type Tyrosine-Protein Phosphatase Epsilon concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Receptor-Type Tyrosine-Protein Phosphatase Epsilon (PTPRE) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.07 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P49446 |
| Gene ID | 19267 |
| Alias | PTPE,HPTPE,R-PTP-EPSILON,Protein-tyrosine phosphatase epsilon,Receptor-type tyrosine-protein phosphatase epsilon |
| Background | Elisa kits for PTPRE |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
PTPRE is a receptor-like protein tyrosine phosphatase that plays essential roles in cellular signaling, particularly in hematopoietic and neuronal systems. Structurally, PTPRE exists as two isoforms: a transmembrane receptor-type protein (RPTPε) and a non-receptor, intracellular cytoplasmic form (cyt-PTPε). Both isoforms share a common catalytic domain but differ in localization and functional regulation. PTPRE is involved in modulating signaling pathways such as those mediated by Src family kinases, integrins, and MAPK pathways. It influences osteoclast differentiation, insulin signaling, and energy metabolism. In the nervous system, PTPRE regulates ion channel activity and neuronal excitability. Dysregulation of PTPRE has been linked to metabolic disorders, including insulin resistance, and its overexpression can contribute to oncogenic signaling pathways in certain cancers.
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anti- PTPRE antibody
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Several alternatively spliced transcript variants of this gene have been reported, at least two of which encode a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokine-induced SATA signaling, as well as the activation of voltage-gated K+ channels.
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Receptor-Type Tyrosine-Protein Phosphatase Epsilon (PTPRE) Antibody
PTPRE Antibody is a Rabbit Polyclonal Antibody against PTPRE.
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Receptor-Type Tyrosine-Protein Phosphatase Epsilon (PTPRE) Antibody
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of this gene have been reported, one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels. [provided by RefSeq].
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