Mouse Ras-related protein Rab-43 (RAB42) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Mouse Ras-related protein Rab-43 (RAB42) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx541168
tested applications
ELISA
Description
Mouse Ras-related protein Rab-43 (RAB42) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Ras-related protein Rab-43 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Ras-related protein Rab-43 (RAB42) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q0PD08 |
| Gene ID | 242681 |
| Alias | Ras-related protein Rab-42 |
| Background | Elisa kits for RAB42 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
RAB42, member RAS oncogene family (RAB42) is another member of the RAB family of small GTPases that plays a key role in vesicular trafficking. RAB42 is primarily involved in regulating the movement of vesicles from the Golgi apparatus to endosomal compartments, as well as in the recycling of membrane proteins. This protein helps ensure the proper sorting and transport of cellular components such as proteins, lipids, and other molecules, facilitating processes like endocytosis, exocytosis, and receptor recycling. In neurons, RAB42 has been shown to contribute to the trafficking of synaptic vesicles, playing a crucial role in neurotransmitter release and synaptic plasticity. Dysregulation of RAB42’s function can lead to disruptions in vesicular trafficking and protein homeostasis, contributing to cellular dysfunction. Its role in the regulation of membrane-bound proteins links RAB42 to diseases such as cancer, where abnormal vesicular trafficking and altered receptor signaling drive tumor growth and metastasis. Additionally, RAB42 is involved in autophagy, which is vital for cellular quality control, and its malfunction may contribute to neurodegenerative disorders, where impaired autophagic processes lead to the accumulation of damaged proteins and organelles, ultimately resulting in cell death.
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