Mouse Ras-related protein Rab-23 (RAB23) ELISA Kit

Product specifications

ELISA Kits

Ras-related protein Rab-23 (RAB23)

Mouse

Colorimetric

Quantitative

0.156 ng/ml - 10 ng/ml

Optimal dilutions/concentrations should be determined by the end user.

96 tests

Lyophilized

ELISA

Tissue homogenates, cell lysates and other biological fluids.

Shipped within 5-15 working days. The validity for this kit is 6 months.

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.

No

P35288

HSPC137,Ras-related protein Rab-23

Elisa kits for RAB23

RUO

Validity: The validity for this kit is 6 months.

This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

RAB23, member RAS oncogene family (RAB23) is a small GTPase that regulates the trafficking of intracellular vesicles and plays a role in the movement of molecules between the endosomal system and other cellular compartments, including the Golgi apparatus and plasma membrane RAB23 has been shown to participate in the process of autophagy, where it helps in the sorting and degradation of cellular materials via the lysosomal pathway, ensuring that damaged or unwanted components are properly processed and removed from the cell This function links RAB23 to cellular stress responses, maintaining cellular integrity and preventing the accumulation of damaged proteins and organelles Additionally, RAB23 is involved in regulating the function of the sonic hedgehog signaling pathway, which is critical for development and the control of cellular proliferation RAB23’s dysfunction is linked to various genetic disorders, including craniofacial malformations, where defects in its trafficking function disrupt proper cellular signaling and tissue development Furthermore, RAB23 is involved in cancer biology, where aberrant vesicular trafficking contributes to uncontrolled cell growth, tumor progression, and metastasis

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