Mouse Ragulator complex protein LAMTOR2 (LAMTOR2) ELISA Kit

Este producto es parte de Ragulator complex protein LAMTOR
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715€ (96 tests)

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935106861
info@markelab.com
name
Mouse Ragulator complex protein LAMTOR2 (LAMTOR2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx531699
tested applications
ELISA

Description

Mouse Ragulator complex protein LAMTOR2 (LAMTOR2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Ragulator complex protein LAMTOR2 concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Ragulator complex protein LAMTOR2 (LAMTOR2)
Reactivity
Mouse
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q9JHS3
Gene ID
83409
Alias
ENDAP,HSPC003,MAPBPIP,MAPKSP1AP,ROBLD3,Ragulator2,p14,Endosomal adaptor protein p14,late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
Background
Elisa kits for LAMTOR2
Status
RUO
Note
Validity: The validity for this kit is 6 months.

This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Ragulator complex protein LAMTOR2 is a key component of the Ragulator complex, which anchors Rag GTPases to the lysosomal membrane, facilitating mTORC1 activation in response to amino acid availability LAMTOR2 works alongside other Ragulator subunits to enable the recruitment and activation of mTORC1, a master regulator of cellular metabolism, growth, and autophagy LAMTOR2 also plays a role in endosomal-lysosomal trafficking and cellular nutrient sensing Studies show that LAMTOR2 is critical for immune cell function, as its loss impairs mTORC1 signaling and compromises T-cell activation and proliferation Dysregulation of LAMTOR2 expression has been implicated in cancer, where disrupted mTOR signaling promotes tumor cell survival and metabolic reprogramming Additionally, defects in LAMTOR2 are associated with lysosomal storage disorders and developmental abnormalities, emphasizing its role in cellular homeostasis, autophagy, and organismal development

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