Mouse Ragulator complex protein LAMTOR2 (LAMTOR2) ELISA Kit

Este producto es parte de Ragulator complex protein LAMTOR
Mouse Ragulator complex protein LAMTOR2 (LAMTOR2) ELISA Kit

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935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for LAMTOR2

proveedor

Abbexa

reference

abx531699

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse Ragulator complex protein LAMTOR2 (LAMTOR2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Ragulator complex protein LAMTOR2 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

Ragulator complex protein LAMTOR2 is a key component of the Ragulator complex, which anchors Rag GTPases to the lysosomal membrane, facilitating mTORC1 activation in response to amino acid availability LAMTOR2 works alongside other Ragulator subunits to enable the recruitment and activation of mTORC1, a master regulator of cellular metabolism, growth, and autophagy LAMTOR2 also plays a role in endosomal-lysosomal trafficking and cellular nutrient sensing Studies show that LAMTOR2 is critical for immune cell function, as its loss impairs mTORC1 signaling and compromises T-cell activation and proliferation Dysregulation of LAMTOR2 expression has been implicated in cancer, where disrupted mTOR signaling promotes tumor cell survival and metabolic reprogramming Additionally, defects in LAMTOR2 are associated with lysosomal storage disorders and developmental abnormalities, emphasizing its role in cellular homeostasis, autophagy, and organismal development

Características del producto

category

ELISA Kits


immunogen target

Ragulator complex protein LAMTOR2 (LAMTOR2)


reactivity

Mouse


test range

0.156 ng/ml - 10 ng/ml


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

ENDAP,HSPC003,MAPBPIP,MAPKSP1AP,ROBLD3,Ragulator2,p14,Endosomal adaptor protein p14,late endosomal/lysosomal adaptor, MAPK and MTOR activator 2


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

LAMTOR2


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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