Mouse Ragulator complex protein LAMTOR2 (LAMTOR2) ELISA Kit
715€ (96 tests)
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name
Mouse Ragulator complex protein LAMTOR2 (LAMTOR2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx531699
tested applications
ELISA
Description
Mouse Ragulator complex protein LAMTOR2 (LAMTOR2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Ragulator complex protein LAMTOR2 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Ragulator complex protein LAMTOR2 (LAMTOR2) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9JHS3 |
| Gene ID | 83409 |
| Alias | ENDAP,HSPC003,MAPBPIP,MAPKSP1AP,ROBLD3,Ragulator2,p14,Endosomal adaptor protein p14,late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 |
| Background | Elisa Kits for: LAMTOR2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Descripción
Ragulator complex protein LAMTOR2 is a key component of the Ragulator complex, which anchors Rag GTPases to the lysosomal membrane, facilitating mTORC1 activation in response to amino acid availability LAMTOR2 works alongside other Ragulator subunits to enable the recruitment and activation of mTORC1, a master regulator of cellular metabolism, growth, and autophagy LAMTOR2 also plays a role in endosomal-lysosomal trafficking and cellular nutrient sensing Studies show that LAMTOR2 is critical for immune cell function, as its loss impairs mTORC1 signaling and compromises T-cell activation and proliferation Dysregulation of LAMTOR2 expression has been implicated in cancer, where disrupted mTOR signaling promotes tumor cell survival and metabolic reprogramming Additionally, defects in LAMTOR2 are associated with lysosomal storage disorders and developmental abnormalities, emphasizing its role in cellular homeostasis, autophagy, and organismal development
