LAMTOR2 Protein

Este producto es parte de Ragulator complex protein LAMTOR
Product Graph
234€ (2 µg)

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935106861
info@markelab.com
name
LAMTOR2 Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx262612
tested applications
SDS-PAGE

Description

LAMTOR2 is a recombinant protein.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
LAMTOR2
Conjugation
Unconjugated
Expression
Recombinant
Purity
> 90% (SDS-PAGE)
Size 1
2 µg
Size 2
10 µg
Size 3
1 mg
Form
Liquid
Tested Applications
SDS-PAGE
Availability
Shipped within 5-10 working days.
Dry Ice
No
UniProt ID
Q9Y2Q5
Alias
ENDAP,HSPC003,MAPBPIP,MAPKSP1AP,ROBLD3,Ragulator2,p14,Endosomal adaptor protein p14,late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
Background
Protein LAMTOR2
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Ragulator complex protein LAMTOR2 is a key component of the Ragulator complex, which anchors Rag GTPases to the lysosomal membrane, facilitating mTORC1 activation in response to amino acid availability LAMTOR2 works alongside other Ragulator subunits to enable the recruitment and activation of mTORC1, a master regulator of cellular metabolism, growth, and autophagy LAMTOR2 also plays a role in endosomal-lysosomal trafficking and cellular nutrient sensing Studies show that LAMTOR2 is critical for immune cell function, as its loss impairs mTORC1 signaling and compromises T-cell activation and proliferation Dysregulation of LAMTOR2 expression has been implicated in cancer, where disrupted mTOR signaling promotes tumor cell survival and metabolic reprogramming Additionally, defects in LAMTOR2 are associated with lysosomal storage disorders and developmental abnormalities, emphasizing its role in cellular homeostasis, autophagy, and organismal development

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