Mouse PTB Domain Containing Engulfment Adapter Protein 1 (GULP1) ELISA Kit

Este producto es parte de GULP engulfment adaptor PTB domain containing 1
Mouse PTB Domain Containing Engulfment Adapter Protein 1 (GULP1) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for GULP1

proveedor

Abbexa

reference

abx389492

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse PTB Domain Containing Engulfment Adapter Protein 1 (GULP1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse GULP1 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

GULP1 is an adaptor protein containing a phosphotyrosine-binding (PTB) domain that mediates signal transduction in cell engulfment, phagocytosis, and apoptotic cell clearance. It interacts with transmembrane receptors like integrins and members of the engulfment pathway, including the CED-1 homologs. GULP1 facilitates actin cytoskeletal rearrangement by bridging receptors to downstream signaling proteins during phagosome formation. It is essential for apoptotic cell removal and has roles in cell migration and lipid homeostasis. GULP1 is expressed in macrophages, epithelial cells, and neurons, where it regulates tissue remodeling and cellular debris clearance. Dysregulation is linked to impaired phagocytosis, inflammatory diseases, and neurodegenerative disorders. Studies in knockout models highlight its role in maintaining immune homeostasis and preventing chronic inflammation.

Características del producto

category

ELISA Kits


immunogen target

PTB Domain Containing Engulfment Adapter Protein 1 (GULP1)


reactivity

Mouse


test range

78 pg/ml - 5000 pg/ml


sensitivity

< 46.9 pg/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

GULP1,CED6,GULP,CED-6


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

GULP1


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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