Mouse Protein Tyrosine Phosphatase Receptor Type Z (PTPRZ) Protein

221€ (10 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Mouse Protein Tyrosine Phosphatase Receptor Type Z (PTPRZ) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx650364
tested applications
WB, SDS-PAGE
Description
Mouse PTPRZ Protein is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Proteins and Peptides |
Immunogen Target | Protein Tyrosine Phosphatase Receptor Type Z (PTPRZ) |
Host | E. coli |
Origin | Mouse |
Conjugation | Unconjugated |
Observed MW | Molecular Weight: Calculated MW: 18.8 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Leu32-Phe163 Tag: N-terminal His tag |
Expression | Recombinant |
Purity | > 95% |
Size 1 | 10 µg |
Size 2 | 50 µg |
Size 3 | 100 µg |
Size 4 | 200 µg |
Size 5 | 500 µg |
Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
Tested Applications | WB, SDS-PAGE |
Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
Availability | Shipped within 5-7 working days. |
Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | B9EKR1 |
Alias | PTPZ,HPTPZ,PTP18,PTPRZ,RPTPB,HPTPzeta,PTP-ZETA,RPTPbeta,phosphacan,R-PTP-zeta-2,Protein-tyrosine phosphatase receptor type Z polypeptide 1,Protein-tyrosine phosphatase receptor type Z polypeptide 2,Receptor-type tyrosine-protein phosphatase zeta |
Background | Protein PTPRZ1 |
Status | RUO |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
PTPRZ1, also known as RPTPζ, is a receptor-type protein tyrosine phosphatase highly expressed in the central nervous system, particularly in glial cells and neurons. Structurally, PTPRZ1 consists of extracellular carbonic anhydrase-like and fibronectin type III domains, a single transmembrane domain, and two intracellular phosphatase domains. PTPRZ1 regulates cell proliferation, differentiation, and migration, particularly in the context of neural development and repair. It acts as a receptor for pleiotrophin and midkine, growth factors involved in neuroprotection and neural plasticity. PTPRZ1 is crucial for maintaining oligodendrocyte function and myelination in the CNS. Dysregulation or overexpression of PTPRZ1 is associated with glioblastomas, where it promotes cell migration and survival. It is also implicated in neuropsychiatric conditions such as schizophrenia due to its role in synaptic regulation and plasticity. PTPRZ1’s multifunctionality underscores its significance in neural development, repair, and tumor biology.
Related Products

Human PTPRZ1 (Receptor-type tyrosine-protein phosphatase zeta) ELISA Kit
Ver Producto
PTPRZ1 antibody
Protein tyrosine phosphatase that negatively regulates oligodendrocyte precursor proliferation in the embryonic spinal cord. Required for normal differentiation of the precursor cells into mature, fully myelinating oligodendrocytes. May play a role in protecting oligondendrocytes against apoptosis. May play a role in the establishment of contextual memory, probably via the dephosphorylation of proteins that are part of important signaling cascades(By similarity).
Ver Producto
Protein Tyrosine Phosphatase, Receptor Type Z1 (PTPRZ1) Antibody
Rabbit polyclonal antibody against PTPRZ1 protein. Immunogen region is N-terminal.
Ver Producto