Mouse Protein Argonaute 3 / EIF2C3 (AGO3) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Mouse Protein Argonaute 3 / EIF2C3 (AGO3) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx501295
tested applications
ELISA
Description
Mouse Protein Argonaute 3 / EIF2C3 (AGO3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Protein Argonaute 3 / EIF2C3 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Protein Argonaute 3 / EIF2C3 (AGO3) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.07 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q8CJF9 |
| Gene ID | 214150 |
| Alias | EIF2C3 |
| Background | Elisa kits for AGO3 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
AGO3 is a member of the Argonaute protein family, playing a role in RNA-induced silencing complex (RISC)-mediated gene regulation. Similar to other Argonaute proteins, AGO3 contains a PAZ domain, which binds the 3' end of small RNAs, and a PIWI domain, but it lacks significant catalytic slicer activity. AGO3 is primarily involved in microRNA (miRNA)-mediated translational repression, aiding in the recruitment of other silencing machinery to target mRNAs. Although less characterized than AGO1 and AGO2, AGO3 is expressed ubiquitously and contributes to post-transcriptional gene silencing in processes such as developmental regulation, stress responses, and immune function. Dysregulation of AGO3 is associated with diseases such as cancer, where altered miRNA activity impacts oncogenic or tumor suppressor pathways, though its precise roles remain under investigation.
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