Mouse Programmed Cell Death 1 Ligand 1 (CD274) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
618.75€ (96 tests)
Elisa Kits CD274
proveedor
Abbexareference
abx154512Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Programmed Cell Death Protein 1 Ligand 1 / PD-L1 (CD274) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Programmed Cell Death Protein 1 Ligand 1 / PD-L1 (CD274) concentrations in serum, plasma, tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of PD-L1 (PD-L1)No significant cross-reactivity or interference between PD-L1 (PD-L1) and analogues was observed.
Background
CD274 molecule, also known as Programmed Death-Ligand 1 (PD-L1), is a critical component in the immune checkpoint pathway. Encoded by the CD274 gene located on chromosome 9p24.1, PD-L1 is primarily expressed on the surface of various cell types, including immune cells (such as T cells, B cells, dendritic cells, and macrophages) and non-immune cells (including epithelial and endothelial cells). Its expression can be upregulated in response to inflammatory signals, particularly interferon-gamma (IFN-γ). PD-L1 plays a vital role in maintaining immune homeostasis and preventing autoimmunity by regulating the activity of T cells. PD-L1 gained significant attention in cancer immunotherapy due to its role in tumor immune evasion. Many tumors exploit the PD-1/PD-L1 pathway to suppress anti-tumor immune responses, allowing cancer cells to escape immune surveillance
Características del producto
category
ELISA Kits
immunogen target
Programmed Cell Death 1 Ligand 1 (CD274)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.07 ng/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Serum,Plasma,Tissue homogenates,Other biological fluids
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
B7-H,B7H1,PDL,PD-L1,hPD-L1,PDCD1L1,PDCD1LG1,B7 homolog 1,PDCD1 ligand 1,Programmed death ligand 1,Programmed cell death 1 ligand 1
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
CD274
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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