Mouse Platelet Derived Growth Factor Receptor Like Protein (PDGFRL) Protein
234€ (10 µg)
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935106861
info@markelab.com
name
Mouse Platelet Derived Growth Factor Receptor Like Protein (PDGFRL) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx167975
tested applications
WB, SDS-PAGE
Description
Platelet Derived Growth Factor Receptor Like Protein is a recombinant Mouse protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Platelet Derived Growth Factor Receptor Like Protein (PDGFRL) |
| Host | E. coli |
| Origin | Mouse |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 43.3 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Gln22-Ser375 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | PDGRL,PRLTS,PDGF receptor beta-like tumor suppressor,PDGFR-like protein |
| Background | Protein PDGFRL |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Platelet derived growth factor receptor like (PDGFRL) lacks intrinsic kinase activity and is thought to function in the regulation of extracellular matrix components and intercellular communication although its precise role is less defined compared to PDGFRA and PDGFRB mutations in PDGFRL have been linked to tumor suppressor activity in colorectal and gastric cancers suggesting it may act as a modulator of growth factor signaling networks its reduced expression has been correlated with increased tumor invasiveness and metastasis in some cancers indicating its potential importance in maintaining cellular homeostasis ongoing research seeks to clarify its role in cellular signaling and its impact on cancer progression and therapeutic resistance.
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