Mouse Plasma Protease C1 Inhibitor / C1INH (SERPING1) ELISA Kit
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935106861
info@markelab.com
Precio
585€ (96 tests)
Elisa kits for SERPING1
proveedor
Abbexareference
abx054431Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Plasma Protease C1 Inhibitor / C1INH (SERPING1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Plasma Protease C1 Inhibitor / C1INH (SERPING1) concentrations in serum, plasma, tissue homogenates, cell lysates and other biological fluids.
Background
SERPING1, also known as C1 esterase inhibitor (C1-INH), is a serine protease inhibitor that plays a critical role in regulating the complement system, a part of the immune response. SERPING1 is primarily responsible for controlling the activation of the C1 complex in the classical pathway of complement activation. Beyond complement regulation, it also inhibits several other proteases involved in the coagulation, fibrinolytic, and kinin-generating systems. SERPING1 mutations or deficiencies are strongly linked to hereditary angioedema (HAE), a potentially life-threatening condition characterized by uncontrolled swelling. SERPING1 is an important therapeutic target in diseases where inappropriate immune activation or excessive protease activity leads to tissue damage or inflammation. It is mainly synthesized in the liver and secreted into the bloodstream, where it circulates and exerts its regulatory effects.
Características del producto
category
ELISA Kits
immunogen target
Plasma Protease C1 Inhibitor / C1INH (SERPING1)
reactivity
Mouse
test range
3.125 ng/ml - 200 ng/ml
sensitivity
1.88 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Serum, plasma, tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
C1IN,C1NH,HAE1,HAE2,C1INH,Plasma protease C1 inhibitor,C1 esterase inhibitor,C1-inhibiting factor
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
SERPING1
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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