Mouse Pituitary Adenylate Cyclase-Activating Polypeptide / PACAP (ADCYAP1) ELISA Kit

Este producto es parte de ADCYAP1 - adenylate cyclase activating polypeptide 1 ( RECEPTOR)
Mouse Pituitary Adenylate Cyclase-Activating Polypeptide / PACAP (ADCYAP1) ELISA Kit
702€ (96 tests)

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Name
Mouse Pituitary Adenylate Cyclase-Activating Polypeptide / PACAP (ADCYAP1) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx254316
Tested Applications
ELISA

Description

Mouse Pituitary Adenylate Cyclase-Activating Polypeptide / PACAP (ADCYAP1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Pituitary Adenylate Cyclase-Activating Polypeptide / PACAP (ADCYAP1) concentrations in serum, plasma and other biological fluids.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
ELISA Kits
Immunogen Target
Pituitary Adenylate Cyclase-Activating Polypeptide / PACAP (ADCYAP1)
Reactivity
Mouse
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Competitive
Test Range
24.7 pg/ml - 2000 pg/ml
Sensitivity
< 9.20 pg/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Serum, plasma and other biological fluids.
Availability
Shipped within 5-7 working days.
Storage
Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
O70176
Gene ID
11516
Alias
PACAP
Background
Elisa Kits for: ADCYAP1
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Background

Adenylate Cyclase Activating Polypeptide 1 (ADCYAP1) is a neuropeptide that acts as a ligand for its receptor, ADCYAP1 receptor. It plays crucial roles in regulating various physiological processes, including neurotransmission, neuroprotection, and modulation of the stress response. The ADCYAP1 receptor, also known as PAC1 receptor, is widely distributed throughout the central nervous system and peripheral tissues, indicating its diverse functions. Upon binding of ADCYAP1 to its receptor, intracellular signaling pathways are activated, leading to the production of cyclic adenosine monophosphate (cAMP) and subsequent activation of protein kinase A (PKA) and other downstream effectors. This signaling cascade influences synaptic transmission, neuronal excitability, and cellular responses to stressors. Dysregulation of ADCYAP1 signaling has been implicated in various neurological and psychiatric disorders, including anxiety, depression, and neurodegenerative diseases. Understanding the mechanisms underlying ADCYAP1 receptor activation provides insights into its physiological functions and potential therapeutic targets for neurological and psychiatric disorders. Ongoing research aims to elucidate the roles of ADCYAP1 signaling in health and disease, paving the way for the development of novel treatment strategies.

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