Mouse Photoreceptor-specific nuclear receptor (NR2E3) ELISA Kit

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Description
Mouse Photoreceptor-specific nuclear receptor (NR2E3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Photoreceptor-specific nuclear receptor concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
Category | ELISA Kits |
Immunogen Target | Photoreceptor-specific nuclear receptor (NR2E3) |
Reactivity | Mouse |
Detection Method | Colorimetric |
Assay Data | Quantitative |
Assay Type | Sandwich |
Test Range | 0.156 ng/ml - 10 ng/ml |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Size 1 | 96 tests |
Form | Lyophilized |
Tested Applications | ELISA |
Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
Dry Ice | No |
UniProt ID | Q9QXZ7 |
Gene ID | 23958 |
Alias | PNR,RNR,rd7,ESCS,RP37,Retina-specific nuclear receptor,Photoreceptor-specific nuclear receptor |
Background | Elisa kits for NR2E3 |
Status | RUO |
Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Nuclear receptor subfamily 2 group E member 3 (NR2E3), also known as photoreceptor-specific nuclear receptor, is a nuclear receptor involved in the regulation of retinal development and the function of photoreceptors in the eye NR2E3 is specifically expressed in the retina, where it regulates the differentiation of photoreceptor cells, including rods and cones It plays a critical role in the development of the retina by influencing the expression of genes involved in the differentiation and maintenance of photoreceptors, which are essential for vision NR2E3 also controls the transcriptional network that governs the survival of retinal cells and the response to light Inherited mutations in NR2E3 are associated with retinal degenerative diseases, such as retinitis pigmentosa, which leads to progressive vision loss by impairing photoreceptor function In addition, NR2E3’s role in regulating the development of other retinal cell types and maintaining visual function makes it an important factor in ocular health and a potential target for therapeutic interventions in retinal diseases
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