Mouse Phosphotidylinositol phosphatase PTPRQ (PTPRQ) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Mouse Phosphotidylinositol phosphatase PTPRQ (PTPRQ) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx514795
tested applications
ELISA
Description
Mouse Phosphotidylinositol phosphatase PTPRQ (PTPRQ) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Phosphotidylinositol phosphatase PTPRQ concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Phosphotidylinositol phosphatase PTPRQ (PTPRQ) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P0C5E4 |
| Alias | DFNA73,DFNB84,DFNB84A,PTPGMC1,R-PTP-Q,Receptor-type tyrosine-protein phosphatase Q,Phosphatidylinositol phosphatase PTPRQ |
| Background | Elisa kits for PTPRQ |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
PTPRQ is a receptor-like protein tyrosine phosphatase that plays critical roles in hair cell function, auditory processes, and cellular signaling. Structurally, PTPRQ contains extracellular domains, a single transmembrane region, and an intracellular phosphatase domain with enzymatic activity. It is primarily expressed in sensory hair cells of the inner ear, where it regulates the structure and function of stereocilia, specialized actin-rich projections responsible for mechanotransduction. PTPRQ is essential for maintaining hair cell integrity and hearing function by modulating phosphatidylinositol signaling and dephosphorylating key targets. Mutations in PTPRQ are associated with autosomal recessive non-syndromic hearing loss, underscoring its importance in auditory physiology. Beyond the ear, PTPRQ also contributes to cellular adhesion, signaling, and cytoskeletal dynamics. Its dysfunction highlights its role in sensory processes and cellular regulation.
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