Mouse Phosphotidylinositol phosphatase PTPRQ (PTPRQ) ELISA Kit
715€ (96 tests)
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Name
Mouse Phosphotidylinositol phosphatase PTPRQ (PTPRQ) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx514795
Tested Applications
ELISA
Description
Mouse Phosphotidylinositol phosphatase PTPRQ (PTPRQ) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Phosphotidylinositol phosphatase PTPRQ concentrations in tissue homogenates, cell lysates and other biological fluids.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Immunogen Target | Phosphotidylinositol phosphatase PTPRQ (PTPRQ) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P0C5E4 |
| Alias | DFNA73,DFNB84,DFNB84A,PTPGMC1,R-PTP-Q,Receptor-type tyrosine-protein phosphatase Q,Phosphatidylinositol phosphatase PTPRQ |
| Background | Elisa Kits for: PTPRQ |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Background
PTPRQ is a receptor-like protein tyrosine phosphatase that plays critical roles in hair cell function, auditory processes, and cellular signaling. Structurally, PTPRQ contains extracellular domains, a single transmembrane region, and an intracellular phosphatase domain with enzymatic activity. It is primarily expressed in sensory hair cells of the inner ear, where it regulates the structure and function of stereocilia, specialized actin-rich projections responsible for mechanotransduction. PTPRQ is essential for maintaining hair cell integrity and hearing function by modulating phosphatidylinositol signaling and dephosphorylating key targets. Mutations in PTPRQ are associated with autosomal recessive non-syndromic hearing loss, underscoring its importance in auditory physiology. Beyond the ear, PTPRQ also contributes to cellular adhesion, signaling, and cytoskeletal dynamics. Its dysfunction highlights its role in sensory processes and cellular regulation.
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