Mouse PHD Finger Protein 6 (PHF6) ELISA Kit

Este producto es parte de PHF - PHD finger protein
Mouse PHD Finger Protein 6 (PHF6) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for PHF6

proveedor

Abbexa

reference

abx538672

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse PHD Finger Protein 6 (PHF6) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse PHD Finger Protein 6 (PHF6) concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

PHF6 is a PHD finger domain-containing protein that functions in transcriptional regulation, chromatin remodeling, and cell cycle control. It interacts with components of chromatin-modifying complexes to facilitate gene silencing or activation, depending on cellular context. PHF6 is expressed in neural and hematopoietic tissues, where it regulates processes such as neurodevelopment, cell proliferation, and differentiation. Mutations in PHF6 are associated with Börjeson-Forssman-Lehmann syndrome, a neurodevelopmental disorder characterized by intellectual disability, epilepsy, and craniofacial abnormalities. PHF6 is also implicated in hematological cancers, including T-cell leukemia, where its loss of function disrupts chromatin organization and transcriptional regulation. Knockout studies demonstrate defects in neuronal development, impaired cell cycle progression, and increased genomic instability, highlighting its essential role in chromatin regulation, neurodevelopment, and disease pathogenesis.

Características del producto

category

ELISA Kits


immunogen target

PHD Finger Protein 6 (PHF6)


reactivity

Mouse


test range

0.156 ng/ml - 10 ng/ml


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

PHF6,CENP-31,KIAA1823,PHD-like zinc finger protein


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

PHF6


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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