Mouse PHD finger protein 23 (PHF23) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Mouse PHD finger protein 23 (PHF23) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx538664
tested applications
ELISA
Description
Mouse PHD finger protein 23 (PHF23) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse PHD finger protein 23 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | PHD finger protein 23 (PHF23) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.06 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q8BSN5 |
| Gene ID | 78246 |
| Alias | hJUNE-1b,PDH-containing protein JUNE-1 |
| Background | Elisa kits for PHF23 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
PHF23 is a chromatin-associated protein with a PHD finger domain that recognizes methylated histones, particularly H3K4me3, to regulate transcriptional activation and chromatin dynamics. It functions as a transcriptional co-activator by recruiting chromatin-modifying enzymes and transcriptional machinery to specific genomic loci, facilitating gene expression during cell proliferation and differentiation. PHF23 is highly expressed in hematopoietic and epithelial tissues, where it regulates pathways associated with cellular survival, stress response, and apoptosis. Dysregulation of PHF23 has been linked to leukemias and solid tumors, where it promotes abnormal proliferation and disrupts epigenetic regulation. Functional studies indicate that loss of PHF23 results in defects in histone recognition, impaired transcriptional activation, and altered cellular proliferation, emphasizing its critical role in maintaining transcriptional regulation, chromatin architecture, and cellular homeostasis.
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