Mouse PHD finger protein 14 (PHF14) ELISA Kit

Este producto es parte de PHF - PHD finger protein
Mouse PHD finger protein 14 (PHF14) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for PHF14

proveedor

Abbexa

reference

abx538655

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse PHD finger protein 14 (PHF14) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse PHD finger protein 14 concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.


Background

PHF14 is a nuclear protein that contains a PHD domain and is involved in chromatin-mediated gene regulation. It acts as a transcriptional regulator by binding to methylated histones, particularly H3K4me3, and recruiting chromatin modifiers to control gene expression. PHF14 regulates processes such as cell proliferation, differentiation, and tissue remodeling, particularly in fibroblasts and epithelial cells. It is widely expressed in embryonic and adult tissues, where it modulates developmental programs, tissue repair, and extracellular matrix organization. Dysregulation of PHF14 is linked to lung fibrosis, kidney disorders, and cancer, where it promotes abnormal proliferation and tissue remodeling by altering transcriptional programs. Knockout studies reveal defects in fibroblast proliferation, impaired organ development, and disrupted extracellular matrix organization, emphasizing its role in chromatin regulation, tissue homeostasis, and disease pathogenesis.

Características del producto

category

ELISA Kits


immunogen target

PHD finger protein 14 (PHF14)


reactivity

Mouse


test range

0.156 ng/ml - 10 ng/ml


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.


size 1

96 tests


alias

PHF14, KIAA0783


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

PHF14


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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status

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clonality

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