Mouse PHD finger protein 14 (PHF14) ELISA Kit

Este producto es parte de PHF - PHD finger protein
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715€ (96 tests)

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935106861
info@markelab.com
name
Mouse PHD finger protein 14 (PHF14) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx538655
tested applications
ELISA

Description

Mouse PHD finger protein 14 (PHF14) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse PHD finger protein 14 concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
PHD finger protein 14 (PHF14)
Reactivity
Mouse
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q9D4H9
Gene ID
75725
Alias
PHF14, KIAA0783
Background
Elisa kits for PHF14
Status
RUO
Note
Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

PHF14 is a nuclear protein that contains a PHD domain and is involved in chromatin-mediated gene regulation. It acts as a transcriptional regulator by binding to methylated histones, particularly H3K4me3, and recruiting chromatin modifiers to control gene expression. PHF14 regulates processes such as cell proliferation, differentiation, and tissue remodeling, particularly in fibroblasts and epithelial cells. It is widely expressed in embryonic and adult tissues, where it modulates developmental programs, tissue repair, and extracellular matrix organization. Dysregulation of PHF14 is linked to lung fibrosis, kidney disorders, and cancer, where it promotes abnormal proliferation and tissue remodeling by altering transcriptional programs. Knockout studies reveal defects in fibroblast proliferation, impaired organ development, and disrupted extracellular matrix organization, emphasizing its role in chromatin regulation, tissue homeostasis, and disease pathogenesis.

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