Mouse Parathyroid Hormone Receptor 2 (PTH2R) ELISA Kit

Este producto es parte de PTHR - Parathyroid Hormone Receptor
Mouse Parathyroid Hormone Receptor 2 (PTH2R) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

556.25€ (96 tests)

Elisa Kits PTH2R

proveedor

Abbexa

reference

abx352930

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse Parathyroid Hormone Receptor 2 (PTH2R) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Parathyroid Hormone Receptor 2 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

PTH2R is a G protein-coupled receptor activated primarily by tuberoinfundibular peptide of 39 residues (TIP39) and, to a lesser extent, parathyroid hormone (PTH). Unlike PTH1R, PTH2R is not involved in calcium homeostasis but instead regulates neuroendocrine functions, pain signaling, and vasodilation. PTH2R is predominantly expressed in the central nervous system, including the hypothalamus and brainstem, as well as in pancreatic and cardiovascular tissues. It couples to Gs proteins, stimulating adenylate cyclase and increasing intracellular cAMP levels. PTH2R modulates neuropeptide release, pain perception, and stress responses. Emerging evidence suggests its involvement in regulating hypothalamic-pituitary functions and modulating blood flow. Dysregulation of PTH2R signaling is linked to altered pain sensitivity, stress-related disorders, and neuroendocrine dysfunction. Targeting PTH2R has therapeutic potential for managing chronic pain, stress disorders, and cardiovascular regulation, highlighting its role in neuropeptide-mediated signaling.

Características del producto

category

ELISA Kits


immunogen target

Parathyroid Hormone Receptor 2 (PTH2R)


reactivity

Mouse


test range

0.78 ng/ml - 50 ng/ml


sensitivity

0.47 ng/ml


assay type

Sandwich


assay data

Quantitative


detection method

Colorimetric


sample type

Tissue homogenates,Cell lysates,Other biological fluids


size 1

96 tests


alias

PTH2R,PTHR2 


storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit


or code

PTH2R


dry ice

No


NCBI accession

NP_644676.1


note

This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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