Mouse Parathyroid Hormone Receptor 1 (PTH1R) ELISA Kit

Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for PTH1R
proveedor
Abbexareference
abx390155Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Parathyroid Hormone Receptor 1 (PTH1R) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse PTH1R concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
PTH1R is a G protein-coupled receptor activated by parathyroid hormone (PTH) and parathyroid hormone-related peptide (PTHrP). It is primarily expressed in bone, kidney, and cartilage, where it regulates calcium and phosphate homeostasis, bone remodeling, and cartilage development. PTH1R couples to both Gs and Gq proteins, leading to activation of adenylate cyclase (increasing cAMP) and phospholipase C (PLC) pathways. In bone, PTH1R mediates osteoblast activation, enhancing bone formation and resorption in response to PTH. In the kidney, PTH1R regulates calcium reabsorption and phosphate excretion to maintain calcium balance. Dysregulation of PTH1R signaling is associated with hyperparathyroidism, hypoparathyroidism, and bone diseases like osteoporosis. PTH analogs that target PTH1R are used therapeutically to treat osteoporosis and hypoparathyroidism by promoting bone growth and mineral homeostasis. PTH1R’s essential role in calcium regulation and skeletal health makes it a key target for metabolic bone diseases.
Características del producto
category
ELISA Kits
immunogen target
Parathyroid Hormone Receptor 1 (PTH1R)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.094 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
PTH1R,PPR,PTHR,PTHR1,EKNS, PFE
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
PTH1R
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
Quizá le pueda interesar
Human PTH1R(PaRathyroid hormone/paRathyroid hormone-related peptide receptor) ELISA Kit

proveedor
FineTestreference
EH15067reactivity
humanstatus
RUOPrecio a consultar
Ver másParathyroid Hormone Receptor 1 (PTH1R) Antibody

proveedor
Abbexareference
abx001452Tested Applications
WB, IHCreactivity
Human, Mouse, Ratstatus
RUOclonality
PolyclonalPTH1R Antibody is a Rabbit Polyclonal antibody against PTH1R. The protein encoded by this gene is a member of the G-prot...
312€ (60 µl)
Ver másParathyroid Hormone Receptor 1 (PTH1R) Antibody

proveedor
Abbexareference
abx011776Tested Applications
ELISA, IHC, IF/ICCreactivity
Humanstatus
RUOclonality
MonoclonalThe protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for ...
383.5€ (100 µl)
Ver más