Pak4 activates the JNK pathway. Plays a role in the reorganization of the actin cytoskeleton and in the formation of filopodia. Phosphorylates and inactivates the protein phosphatase SSH1, leading to increased inhibitory phosphorylation of the actin binding/depolymerizing factor cofilin. Decreased cofilin activity may lead to stabilization of actin filaments. Phosphorylates ARHGEF2 (By similarity).
Primary Antibodies
Polyclonal
Human, Mouse
Mouse Pak4
Rabbit
Unconjugated
Liquid
ELISA, WB, FCM
Purified through a protein A column, followed by peptide affinity purification.
PBS containing 0.09% sodium azide.
80 µl
400 µl
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Pak4
No
Shipped within 5-10 working days.
This product is for research use only.
Pak4 activates the JNK pathway. Plays a role in the reorganization of the actin cytoskeleton and in the formation of fil...
250€ (80 µl)
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