Mouse Oxytocin Receptor (OXTR) Protein
234€ (10 µg)
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935106861
info@markelab.com
name
Mouse Oxytocin Receptor (OXTR) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx068413
tested applications
WB, SDS-PAGE
Description
Recombinant Oxytocin Receptor (OXTR) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Oxytocin Receptor (OXTR) |
| Host | E. coli |
| Origin | Mouse |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 37.4 kDa Observed MW (SDS-PAGE): 37 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Ala6-Phe75 Tag: N-terminal His tag and GST tag |
| Expression | Recombinant |
| Purity | > 97% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 10 mM PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in 10 mM PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 5% Trehalose. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P97926 |
| Alias | OXTR,OTR,OT-R |
| Background | Protein OXTR |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
OXTR is a G protein-coupled receptor activated by the hormone oxytocin, which plays a central role in childbirth, lactation, and social bonding. OXTR is expressed in various tissues, including the uterus, mammary glands, brain, and heart. In the uterus, oxytocin binds to OXTR to stimulate labor by causing uterine smooth muscle contraction. In lactating women, oxytocin binds to OXTR to facilitate milk ejection. OXTR in the brain is involved in promoting social bonding, maternal behaviors, and emotional responses, and has been implicated in the regulation of anxiety and stress. Dysregulation of OXTR signaling is associated with conditions such as autism spectrum disorder (ASD), where social bonding and empathy are impaired, and postpartum depression, where oxytocin signaling is thought to be altered. Research into OXTR agonists and antagonists holds promise for treating mood disorders, social dysfunction, and enhancing social bonding and attachment.
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