Mouse Osteomodulin (OMD) Protein
1079€ (100 µg)
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935106861
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name
Mouse Osteomodulin (OMD) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx691970
tested applications
SDS-PAGE
Description
Mouse Osteomodulin Protein is a recombinant protein from Mouse produced in HEK293 Cells. A DNA sequence encoding the mouse OMD (NP_036180.1) (Met 1-Ile 423) precusor was expressed, with a C-terminal polyhistidine tag.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Osteomodulin |
| Host | HEK293 cells |
| Origin | Mouse |
| Observed MW | Molecular Weight: 48.8 kDa Sequence Fragment: Met1-Ile423 Tag: C-terminal His tag Validity: The validity for this protein is 12 months. |
| Expression | Recombinant |
| Purity | > 96% (SDS-PAGE) |
| Size 1 | 100 µg |
| Form | |
| Tested Applications | SDS-PAGE |
| Buffer | Lyophilized from sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O35103 |
| NCBI Accession | NP_036180.1 |
| Alias | OSAD,SLRR2C,KSPG osteomodulin,Osteoadherin |
| Background | Protein OMD |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Osteomodulin (OMD) is a small leucine-rich proteoglycan primarily expressed in the bone and cartilage, where it plays a key role in regulating extracellular matrix (ECM) structure and function OMD is involved in bone mineralization, collagen fibril organization, and cartilage development by interacting with collagen and other ECM components It contributes to skeletal integrity and has a significant impact on the mechanical properties of bone, influencing bone strength and elasticity OMD’s expression is upregulated during bone remodeling, and its role in cartilage integrity makes it crucial for joint health and skeletal repair Dysregulation of OMD expression has been associated with bone diseases such as osteogenesis imperfecta and osteoarthritis, where altered ECM composition leads to skeletal deformities and joint degradation Studies also suggest that OMD influences cell signaling pathways, particularly those related to osteoblast differentiation and function, highlighting its broader role in skeletal development and disease
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