Mouse Nucleoporin 37 kDa (NUP37) Protein
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935106861
info@markelab.com
Precio
247€ (10 µg)
Protein NUP37
proveedor
Abbexareference
abx167475Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Nucleoporin 37 kDa Protein is a recombinant Mouse protein expressed in E. coli.
Background
Nucleoporin 37 (NUP37) is another important nucleoporin that contributes to the structure and function of the nuclear pore complex NUP37 interacts with other nucleoporins to form the central channel of the nuclear pore, allowing for the selective exchange of macromolecules between the nucleus and cytoplasm It plays a role in RNA processing and transport, ensuring that RNA molecules are correctly exported from the nucleus to the cytoplasm for protein synthesis NUP37 is also involved in the regulation of cell cycle progression and transcriptional control, as its function in nuclear-cytoplasmic transport affects gene expression and cellular responses to external stimuli Defects in NUP37 have been associated with various disorders, including certain types of cancer and neurodevelopmental diseases, where impaired nuclear pore function disrupts cellular homeostasis and protein synthesis
Características del producto
category
Proteins and Peptides
origin
Mouse
host
E. coli
immunogen target
Nucleoporin 37kDa (NUP37)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 30.7 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Asp87-Thr324 Tag: N-terminal His tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
NUP37
dry ice
No
availability
Shipped within 5-7 working days.
alias
p37,MCPH24,Nup107-160 subcomplex subunit Nup37
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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