Mouse Nucleoporin 37 kDa (NUP37) Protein

Este producto es parte de NUP - nucleoporin
Mouse Nucleoporin 37 kDa (NUP37) Protein

Pida mas información

935106861

info@markelab.com

Precio

247€ (10 µg)

Protein NUP37

proveedor

Abbexa

reference

abx167475

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Nucleoporin 37 kDa Protein is a recombinant Mouse protein expressed in E. coli.


Background

Nucleoporin 37 (NUP37) is another important nucleoporin that contributes to the structure and function of the nuclear pore complex NUP37 interacts with other nucleoporins to form the central channel of the nuclear pore, allowing for the selective exchange of macromolecules between the nucleus and cytoplasm It plays a role in RNA processing and transport, ensuring that RNA molecules are correctly exported from the nucleus to the cytoplasm for protein synthesis NUP37 is also involved in the regulation of cell cycle progression and transcriptional control, as its function in nuclear-cytoplasmic transport affects gene expression and cellular responses to external stimuli Defects in NUP37 have been associated with various disorders, including certain types of cancer and neurodevelopmental diseases, where impaired nuclear pore function disrupts cellular homeostasis and protein synthesis

Características del producto

category

Proteins and Peptides


origin

Mouse


host

E. coli


immunogen target

Nucleoporin 37kDa (NUP37)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 30.7 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Asp87-Thr324 Tag: N-terminal His tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

NUP37


dry ice

No


availability

Shipped within 5-7 working days.


alias

p37,MCPH24,Nup107-160 subcomplex subunit Nup37


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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