Mouse Nucleoporin 160 kDa (NUP160) Protein
247€ (10 µg)
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935106861
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name
Mouse Nucleoporin 160 kDa (NUP160) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx068358
tested applications
WB, SDS-PAGE
Description
Recombinant Nucleoporin 160 kDa (NUP160) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Nucleoporin 160kDa (NUP160) |
| Host | E. coli |
| Origin | Mouse |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 25.2 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Phe11-Val206 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9Z0W3 |
| Alias | NPHS19,nucleoporin 160kDa,Nuclear pore complex protein Nup160 |
| Background | Protein NUP160 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Nucleoporin 160 (NUP160) is a large and essential component of the nuclear pore complex, contributing to the overall architecture and function of the NPC NUP160 is involved in the regulation of nuclear-cytoplasmic transport, particularly in the trafficking of RNA and proteins that are crucial for gene expression, protein synthesis, and cellular signaling It helps maintain the structure of the nuclear pore and facilitates the passage of macromolecules across the nuclear envelope, ensuring the efficiency of molecular exchange NUP160 plays a critical role in regulating the cell cycle, particularly in processes such as mitosis, where it helps control the localization of key regulatory proteins Additionally, NUP160 is linked to the regulation of immune responses and tissue repair, making it an important factor in the body's response to cellular stress and injury Dysregulation of NUP160 has been associated with several diseases, including cancers and immune system disorders, where altered nuclear transport contributes to pathological changes in cell growth, gene regulation, and immune function
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