Mouse Nucleoporin 160 kDa (NUP160) CLIA Kit

Product specifications

CLIA Kits

Nucleoporin 160 kDa (NUP160)

Mouse

Chemiluminescent

Quantitative

Sandwich

31.2 pg/ml - 2000 pg/ml

18.8 pg/ml

Optimal dilutions/concentrations should be determined by the end user.

96 tests

Lyophilized

CLIA

Serum, plasma and other biological fluids.

Shipped within 5-12 working days.

 Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.

No

NPHS19,nucleoporin 160kDa,Nuclear pore complex protein Nup160

CLIA Kits NUP160

RUO

The validity for this kit is 6 months.   This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Nucleoporin 160 (NUP160) is a large and essential component of the nuclear pore complex, contributing to the overall architecture and function of the NPC NUP160 is involved in the regulation of nuclear-cytoplasmic transport, particularly in the trafficking of RNA and proteins that are crucial for gene expression, protein synthesis, and cellular signaling It helps maintain the structure of the nuclear pore and facilitates the passage of macromolecules across the nuclear envelope, ensuring the efficiency of molecular exchange NUP160 plays a critical role in regulating the cell cycle, particularly in processes such as mitosis, where it helps control the localization of key regulatory proteins Additionally, NUP160 is linked to the regulation of immune responses and tissue repair, making it an important factor in the body's response to cellular stress and injury Dysregulation of NUP160 has been associated with several diseases, including cancers and immune system disorders, where altered nuclear transport contributes to pathological changes in cell growth, gene regulation, and immune function

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