NUP160 antibody
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935106861
info@markelab.com
name
NUP160 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab05922
tested applications
ELISA, WB
Description
Involved in poly(A)+ RNA transport.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | nucleoporin 160kDa (NUP160) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 149 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q12769 |
| Gene ID | 23279 |
| Alias | NPHS19,nucleoporin 160kDa,Nuclear pore complex protein Nup160 |
| Background | Antibody anti-NUP160 |
| Status | RUO |
| Note | Mol. Weight 149 kDa |
Descripción
Nucleoporin 160 (NUP160) is a large and essential component of the nuclear pore complex, contributing to the overall architecture and function of the NPC NUP160 is involved in the regulation of nuclear-cytoplasmic transport, particularly in the trafficking of RNA and proteins that are crucial for gene expression, protein synthesis, and cellular signaling It helps maintain the structure of the nuclear pore and facilitates the passage of macromolecules across the nuclear envelope, ensuring the efficiency of molecular exchange NUP160 plays a critical role in regulating the cell cycle, particularly in processes such as mitosis, where it helps control the localization of key regulatory proteins Additionally, NUP160 is linked to the regulation of immune responses and tissue repair, making it an important factor in the body's response to cellular stress and injury Dysregulation of NUP160 has been associated with several diseases, including cancers and immune system disorders, where altered nuclear transport contributes to pathological changes in cell growth, gene regulation, and immune function
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