Mouse Nucleoporin 133 kDa (NUP133) Protein

Name: Mouse Nucleoporin 133 kDa (NUP133) Protein
Brand: Abbexa
SKU: abx068356
Price: 234 EUR
Availability: OnlineOnly

Este producto es parte de NUP - nucleoporin

Pida mas información

935106861

info@markelab.com

Precio

234€ (10 µg)

Protein NUP133

proveedor

Abbexa

reference

abx068356

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Recombinant Nucleoporin 133 kDa (NUP133) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).

Background

Nucleoporin 133 (NUP133) is a nucleoporin involved in the nuclear pore complex, which regulates the selective transport of molecules between the nucleus and cytoplasm NUP133 is essential for the structural integrity of the nuclear pore and is involved in the formation of the central channel that facilitates the trafficking of RNA, proteins, and ribosomal subunits NUP133 plays a critical role in ensuring efficient gene expression by allowing the proper export of mRNA from the nucleus to the cytoplasm for translation Dysregulation of NUP133 has been associated with cellular processes such as the cell cycle, DNA repair, and immune responses It is particularly important for maintaining nuclear function during cell division and ensuring the proper functioning of mitosis NUP133 has also been implicated in cancer, where alterations in nucleocytoplasmic transport contribute to abnormal gene expression and tumor progression Its role in regulating cell cycle checkpoints and maintaining genomic stability makes NUP133 crucial for proper cell function and tissue homeostasis

Características del producto

origin

Mouse

host

E. coli

immunogen target

Nucleoporin 133kDa (NUP133)

host

E. coli

conjugation

Unconjugated

form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.

tested applications

WB, SDS-PAGE

size 1

10 µg

size 2

50 µg

size 3

100 µg

size 4

200 µg

size 5

500 µg

observerd MW

Molecular Weight: Calculated MW: 25.7 kDa Observed MW (SDS-PAGE): 26 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Leu36-His240 Tag: N-terminal His tag

expression

Recombinant

purity

> 95%

buffer

Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300.

storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.

or code

NUP133

dry ice

availability

Shipped within 5-7 working days.

alias

GAMOS8,NPHS18,Hnup133,nucleoporin 133kDa,Nuclear pore complex protein Nup133

uniprot id

https://www.uniprot.org/uniprotkb/Q8R0G9

note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.

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anti- NUP133 antibody

proveedor

FineTest

reference

FNab05920

Tested Applications

ELISA, WB, IHC, IP

reactivity

human,mouse,rat

status

RUO

clonality

polyclonal

Involved in poly(A)+ RNA transport.

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