Mouse Nr3c1(Glucocorticoid receptor) ELISA Kit

Este producto es parte de NR3C - nuclear receptor subfamily 3 group C member
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935106861
info@markelab.com
name
Mouse Nr3c1(Glucocorticoid receptor) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EM0656

Documents del producto

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Data sheet

Product specifications

CategoryELISA Kits
Reactivitymouse
Detection MethodColorimetric
Assay DataQuantitative
Assay TypeSandwich ELISA, Double Antibody
Test Range0.156-10ng/ml
Size 196T
Sample TypeSerum,Plasma,Tissue homogenates,Other biological fluids
AvailabilityShipped within 10-14 working days.
Storage2-8 °C for 6 months
UniProt IDP06537
AliasGR,GCR,GRL,GCCR,GCRST,Glucocorticoid receptor
BackgroundElisa Kits NR3C1
StatusRUO

Nuclear receptor subfamily 3 group C member 1 (NR3C1), also known as the glucocorticoid receptor (GR), is a nuclear receptor that mediates the effects of glucocorticoids, hormones involved in stress response, metabolism, and immune function NR3C1 is activated by glucocorticoids, such as cortisol, and regulates the expression of genes involved in inflammation, immune suppression, and metabolism It is expressed in a variety of tissues, including the liver, immune cells, and brain, where it influences processes such as glucose metabolism, fat storage, and the immune response NR3C1 plays a key role in the body’s response to stress by regulating the hypothalamic-pituitary-adrenal (HPA) axis, which controls the production of cortisol and other stress hormones Dysregulation of NR3C1 signaling has been linked to various diseases, including metabolic syndrome, depression, autoimmune disorders, and cancer, where improper glucocorticoid signaling can contribute to inflammation, altered metabolism, and immune dysfunction GR is also a target for corticosteroid drugs used to treat conditions like asthma, arthritis, and autoimmune diseases

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