Mouse Nr1i3(Nuclear receptor subfamily 1 group I member 3) ELISA Kit
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name
Mouse Nr1i3(Nuclear receptor subfamily 1 group I member 3) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EM0735
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Reactivity | mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 0.313-20ng/ml |
| Size 1 | 96T |
| Sample Type | Serum,Plasma,Tissue homogenates,Other biological fluids |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 6 months |
| UniProt ID | O35627 |
| Alias | CAR,CAR1,MB67,Constitutive activator of retinoid response,Orphan nuclear receptor MB67 |
| Background | Elisa Kits NR1I3 |
| Status | RUO |
Nuclear receptor subfamily 1 group I member 3 (NR1I3), also known as the constitutive androstane receptor (CAR), is a nuclear receptor involved in regulating the metabolism of xenobiotics, drugs, and endogenous compounds CAR is activated by various ligands, including drugs, steroids, and bile acids, and it modulates the expression of genes involved in detoxification and drug metabolism It is primarily expressed in the liver, intestine, and kidneys, where it controls the transcription of genes that enhance the metabolism and clearance of toxins, carcinogens, and drugs CAR plays a key role in regulating liver function, bile acid homeostasis, and the metabolism of fatty acids In addition to its role in detoxification, CAR has been implicated in the regulation of inflammation and immune responses Dysregulation of CAR can contribute to liver disease, altered drug metabolism, and drug toxicity, making it an important receptor for understanding drug interactions and developing strategies to manage liver disorders and improve drug safety
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