Mouse Neuropeptide Y Receptor Y4 (NPY4R) ELISA Kit

Este producto es parte de NPY - Neuropeptide Y Receptor
Mouse Neuropeptide Y Receptor Y4 (NPY4R) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for NPY4R

proveedor

Abbexa

reference

abx390147

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse Neuropeptide Y Receptor Y4 (NPY4R) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse NPY4R concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

NPY4R, also known as the pancreatic polypeptide receptor, is a G protein-coupled receptor activated primarily by pancreatic polypeptide (PP) and, to a lesser extent, by peptide YY (PYY) and neuropeptide Y (NPY). NPY4R is expressed in the hypothalamus, brainstem, and peripheral tissues, particularly in the gastrointestinal tract, pancreas, and adipose tissue. Activation of NPY4R regulates appetite, energy balance, and gastrointestinal function. It couples to Gi/o proteins, inhibiting adenylate cyclase, reducing cAMP levels, and modulating neurotransmission. NPY4R plays a role in reducing food intake and regulating satiety, particularly following meal ingestion. Dysregulation of NPY4R is associated with obesity, metabolic disorders, and impaired pancreatic function. NPY4R agonists are being explored as therapeutic agents for obesity and type 2 diabetes, as enhancing NPY4R signaling can reduce appetite and improve glucose homeostasis. Its role in energy balance and metabolism highlights NPY4R as a promising target for managing obesity and metabolic diseases.

Características del producto

category

ELISA Kits


immunogen target

Neuropeptide Y Receptor Y4 (NPY4R)


reactivity

Mouse


test range

0.156 ng/ml - 10 ng/ml


sensitivity

< 0.094 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

NPY4R,NPY4-R,PP1,PPYR1,Y4,PP1,neuropeptide Y receptor type 4,pancreatic polypeptide receptor 1


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

NPY4R


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


Quizá le pueda interesar

Neuropeptide Y Receptor Type 4 (NPY4R) Antibody

Neuropeptide Y Receptor Type 4 (NPY4R) Antibody

proveedor

Abbexa

reference

abx005705

Tested Applications

WB

reactivity

Human

status

RUO

clonality

Polyclonal

NPY4R Antibody is a Rabbit Polyclonal Antibody against NPY4R.

312€ (60 µl)

Ver más

Neuropeptide Y receptor type 4 (NPY4R) Antibody

Neuropeptide Y receptor type 4 (NPY4R) Antibody

proveedor

Abbexa

reference

abx210685

Tested Applications

ELISA, IHC

reactivity

Human

status

RUO

clonality

Polyclonal

NPY4R Antibody is a Rabbit Polyclonal against NPY4R.

260€ (50 µl)

Ver más

Neuropeptide Y Receptor Type 4 (NPY4R) Antibody

Neuropeptide Y Receptor Type 4 (NPY4R) Antibody

proveedor

Abbexa

reference

abx304945

Tested Applications

ELISA, IHC

reactivity

Human

status

RUO

clonality

Polyclonal

NPY4R Antibody is a Rabbit Polyclonal against NPY4R.

169€ (20 µg)

Ver más