Mouse Neuropeptide Y Receptor Y4 (NPY4R) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for NPY4R
proveedor
Abbexareference
abx390147Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Neuropeptide Y Receptor Y4 (NPY4R) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse NPY4R concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
NPY4R, also known as the pancreatic polypeptide receptor, is a G protein-coupled receptor activated primarily by pancreatic polypeptide (PP) and, to a lesser extent, by peptide YY (PYY) and neuropeptide Y (NPY). NPY4R is expressed in the hypothalamus, brainstem, and peripheral tissues, particularly in the gastrointestinal tract, pancreas, and adipose tissue. Activation of NPY4R regulates appetite, energy balance, and gastrointestinal function. It couples to Gi/o proteins, inhibiting adenylate cyclase, reducing cAMP levels, and modulating neurotransmission. NPY4R plays a role in reducing food intake and regulating satiety, particularly following meal ingestion. Dysregulation of NPY4R is associated with obesity, metabolic disorders, and impaired pancreatic function. NPY4R agonists are being explored as therapeutic agents for obesity and type 2 diabetes, as enhancing NPY4R signaling can reduce appetite and improve glucose homeostasis. Its role in energy balance and metabolism highlights NPY4R as a promising target for managing obesity and metabolic diseases.
Características del producto
category
ELISA Kits
immunogen target
Neuropeptide Y Receptor Y4 (NPY4R)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.094 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
NPY4R,NPY4-R,PP1,PPYR1,Y4,PP1,neuropeptide Y receptor type 4,pancreatic polypeptide receptor 1
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
NPY4R
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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