Mouse Neurobeachin (NBEA) ELISA Kit

Este producto es parte de NBEA - neurobeachin
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715€ (96 tests)

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935106861
info@markelab.com
name
Mouse Neurobeachin (NBEA) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx390009
tested applications
ELISA

Description

Mouse Neurobeachin (NBEA) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse NBEA concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryELISA Kits
Immunogen TargetNeurobeachin (NBEA)
ReactivityMouse
Detection MethodColorimetric
Assay DataQuantitative
Assay TypeSandwich
Test Range78 pg/ml - 5000 pg/ml
Sensitivity< 46.9 pg/ml
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
Size 196 tests
FormLyophilized
Tested ApplicationsELISA
Sample TypeTissue homogenates, cell lysates and other biological fluids.
AvailabilityShipped within 5-12 working days. The validity for this kit is 6 months.
StorageShipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry IceNo
UniProt IDQ9EPN1
Gene ID26422
AliasBCL8B,LYST2,NEDEGE,Protein BCL8B,Lysosomal-trafficking regulator 2
BackgroundElisa kits for NBEA
StatusRUO
NoteValidity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Neurobeachin (NBEA) is a multi-domain protein involved in the regulation of synaptic function, neuronal signaling, and cell adhesion NBEA is particularly abundant in the brain, where it plays a role in neuronal growth, synaptic plasticity, and the maintenance of neuronal structure It interacts with a variety of proteins involved in synaptic signaling and vesicle trafficking, contributing to the organization of the postsynaptic density and the regulation of neurotransmitter receptor trafficking NBEA is essential for the proper function of neurons, particularly in areas involved in learning and memory, and its dysfunction is linked to neurological disorders such as neurodevelopmental disorders and intellectual disability Mutations in NBEA disrupt neuronal connectivity and signaling, leading to impaired cognitive function Understanding NBEA’s role in neuronal health could provide insights into therapies for treating neurodevelopmental and neurodegenerative diseases

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