Mouse Neuregulin 4 (NRG4) Protein

Este producto es parte de NRG - neuregulin
Product Graph
234€ (10 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Mouse Neuregulin 4 (NRG4) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx167365
tested applications
WB, SDS-PAGE

Description

Neuregulin 4 Protein is a recombinant Mouse protein expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Neuregulin 4 (NRG4)
Host
E. coli
Origin
Mouse
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 10.5 kDa  Observed MW (SDS-PAGE): 11 kDa
Concentration: Prior to lyophilization: 200 µg/ml
Sequence Fragment: Met1-Ser62
Tag: N-terminal His tag
Expression
Recombinant
Purity
> 90%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
HRG4,Pro-NRG4,Pro-neuregulin-4 membrane-bound isoform
Background
Protein NRG4
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Neuregulin 4 (NRG4) is a member of the neuregulin family, which consists of growth factors that play critical roles in cell signaling, development, and homeostasis. NRG4 primarily acts through the ErbB family of receptor tyrosine kinases, notably interacting with ErbB4 to initiate downstream signaling pathways. This signaling is involved in a variety of physiological processes, including metabolism, tissue repair, and the regulation of energy balance. Research suggests that NRG4 may have protective roles in metabolic disorders, such as obesity and type 2 diabetes, by modulating insulin sensitivity and inflammatory responses in key tissues like the liver and adipose tissue. Additionally, NRG4's role in neuronal and cardiac development has also been noted, highlighting its importance across diverse biological systems. Further exploration of NRG4's signaling mechanisms may provide valuable insights into therapeutic strategies for metabolic and neurodegenerative diseases.

Related Products

EH3443

Human NRG-4(Neuregulin 4) ELISA Kit

Ver Producto
EM1240

Mouse NRG-4(Neuregulin 4) ELISA Kit

Ver Producto
P6292

Recombinant Human NRG4

Ver Producto