Mouse Neural cell adhesion molecule 2 (NCAM2) ELISA Kit

Este producto es parte de NCAM - neural cell adhesion molecule
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715€ (96 tests)

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935106861
info@markelab.com
name
Mouse Neural cell adhesion molecule 2 (NCAM2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx515948
tested applications
ELISA

Description

Mouse Neural cell adhesion molecule 2 (NCAM2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Neural cell adhesion molecule 2 concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryELISA Kits
Immunogen TargetNeural cell adhesion molecule 2 (NCAM2)
ReactivityMouse
Detection MethodColorimetric
Assay DataQuantitative
Assay TypeSandwich
Test Range0.156 ng/ml - 10 ng/ml
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
Size 196 tests
FormLyophilized
Tested ApplicationsELISA
Sample TypeTissue homogenates, cell lysates and other biological fluids.
AvailabilityShipped within 5-12 working days. The validity for this kit is 6 months.
StorageShipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry IceNo
UniProt IDO35136
AliasNCAM21,N-CAM-2
BackgroundElisa kits for NCAM2
StatusRUO
NoteValidity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Neural Cell Adhesion Molecule 2 (NCAM2), also known as OCAM (Olfactory Cell Adhesion Molecule), is another member of the immunoglobulin (Ig) superfamily that mediates cell adhesion and neuronal connectivity. NCAM2 shares structural similarities with NCAM1, including five Ig-like domains and two fibronectin type III domains in its extracellular region. However, NCAM2 has distinct roles in the olfactory system and brain development. It is highly expressed in olfactory neurons, where it regulates axon guidance and synaptic targeting. NCAM2 is crucial for neuronal differentiation and the establishment of specific neural circuits, particularly in the hippocampus and olfactory bulb. It mediates homophilic binding (interaction with identical molecules) to promote cell adhesion and structural organization. In the brain, NCAM2 is essential for the maintenance of synaptic connections and proper cortical layering.

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