Mouse Myosin Light Chain Kinase 3 (MYLK3) ELISA Kit
715€ (96 tests)
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name
Mouse Myosin Light Chain Kinase 3 (MYLK3) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx534197
tested applications
ELISA
Description
Mouse Myosin Light Chain Kinase 3 (MYLK3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Myosin Light Chain Kinase 3 (MYLK3) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Myosin Light Chain Kinase 3 (MYLK3) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.06 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q3UIZ8 |
| Gene ID | 213435 |
| Alias | MLCK,MLCK2,caMLCK,Cardiac-MyBP-C-associated Ca/CaM kinase,Cardiac-MLCK |
| Background | Elisa kits for MYLK3 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Myosin light chain kinase 3 (MYLK3) is primarily expressed in cardiac muscle, where it plays a pivotal role in modulating heart muscle contraction and relaxation. Similar to MYLK2, MYLK3 phosphorylates the regulatory light chains of myosin II, facilitating efficient cross-bridge cycling and force production during cardiac cycles. MYLK3's activity is also dependent on calcium-calmodulin signaling, linking it to the intracellular calcium fluxes that drive cardiac contractility. MYLK3 is essential for maintaining myocardial function and is implicated in cardiac hypertrophy and heart failure when dysregulated. Emerging research highlights MYLK3's involvement in sarcomere organization and its potential as a therapeutic target for improving cardiac performance in disease settings. Together, MYLK2 and MYLK3 underscore the critical and tissue-specific roles of myosin light chain kinases in muscle physiology.
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