Mouse Myeloid Cell Surface Antigen CD33 (CD33) Protein

Este producto es parte de CD33 molecule
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429€ (20 µg)

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935106861
info@markelab.com
name
Mouse Myeloid Cell Surface Antigen CD33 (CD33) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx692457
tested applications
SDS-PAGE

Description

Mouse CD33 Protein is a recombinant protein from Mouse produced in HEK293 Cells. A DNA sequence encoding the extracellular domain of mouse CD33 (Q63994-1) (Met 1-Glu 240) was fused with a polyhistidine tag at the C-terminus.

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Product specifications

CategoryProteins and Peptides
Immunogen TargetCD33
HostHEK293 cells
OriginMouse
Observed MWMolecular Weight: 26 kDa Sequence Fragment: Met1-Glu240 Tag: C-terminal His tag Validity: The validity for this protein is 12 months.
ExpressionRecombinant
Purity> 92% (SDS-PAGE)
Size 120 µg
Size 250 µg
Form
Tested ApplicationsSDS-PAGE
BufferLyophilized from sterile PBS, pH 7.4.
AvailabilityShipped within 5-15 working days.
StorageAliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDQ63994-1
Aliasp67,SIGLEC3,SIGLEC-3,CD33rSiglec,Sialic acid-binding Ig-like lectin 3,Myeloid cell surface antigen CD33
BackgroundProtein CD33
StatusRUO
NoteThis product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

CD33, also known as Siglec-3 (Sialic acid-binding Ig-like lectin 3), is a transmembrane receptor expressed primarily on cells of myeloid lineage. It belongs to the immunoglobulin (Ig) superfamily and plays a significant role in the regulation of innate immunity. CD33 was first identified in the late 1980s as a marker on acute myeloid leukemia (AML) cells, making it a focal point for research in hematological malignancies. This glycoprotein is encoded by the CD33 gene located on chromosome 19q13.3. CD33 is involved in cellular signaling processes that modulate immune cell function and survival.

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