Mouse Muscle Skeletal Receptor Tyrosine Kinase (MUSK) ELISA Kit

Este producto es parte de MUSK - muscle associated receptor tyrosine kinase
Mouse Muscle Skeletal Receptor Tyrosine Kinase (MUSK) ELISA Kit
715€ (96 tests)

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Name
Mouse Muscle Skeletal Receptor Tyrosine Kinase (MUSK) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx154419
Tested Applications
ELISA

Description

Mouse Muscle Skeletal Receptor Tyrosine Kinase (MUSK) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse MUSK concentrations in tissue homogenates, cell lysates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK)

Documentos del producto

Instrucciones
Descargar
Data sheet
Descargar

Especificaciones del producto

Category
ELISA Kits
Immunogen Target
Muscle Skeletal Receptor Tyrosine Kinase (MUSK)
Reactivity
Mouse
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.156 ng/ml - 10 ng/ml
Sensitivity
< 0.06 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-7 working days.
Storage
Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
Alias
CMS9,FADS,FADS1,Muscle-specific tyrosine-protein kinase receptor,Muscle skeletal receptor tyrosine-protein kinase
Background
Elisa Kits for: MUSK
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Background

Muscle-associated receptor tyrosine kinase (MUSK) is a critical protein in the formation and maintenance of the neuromuscular junction (NMJ), the synapse between motor neurons and muscle fibers. MUSK is essential for the proper functioning of the NMJ, playing a pivotal role in the signaling pathways that govern the assembly and stability of this specialized synapse. The NMJ is crucial for muscle contraction and overall motor function, and disruptions in MUSK function can lead to severe neuromuscular diseases. MUSK is encoded by the MUSK gene, located on chromosome 9 in humans. The protein belongs to the receptor tyrosine kinase family and is highly conserved across species, reflecting its essential role in muscle biology. MUSK activation is tightly regulated and involves interactions with several other proteins, including agrin, low-density lipoprotein receptor-related protein 4 (LRP4), and downstream effectors such as rapsyn.

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