Mouse Microtubule Associated Protein 2 (MAP2) Protein

Este producto es parte de MAP2 - microtubule associated protein 2
Mouse Microtubule Associated Protein 2 (MAP2) Protein

Pida mas información

935106861

info@markelab.com

Precio

234€ (10 µg)

Protein MAP2

proveedor

Abbexa

reference

abx068013

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Recombinant Microtubule Associated Protein 2 (MAP2) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).


Background

Microtubule-associated protein 2 (MAP2) is a protein primarily found in neurons, where it plays a crucial role in stabilizing microtubules, maintaining cell shape, and supporting dendritic development MAP2 is part of a family of microtubule-associated proteins that bind to microtubules and regulate their stability, thereby contributing to the structural integrity of the cytoskeleton In neurons, MAP2 is essential for dendritic growth and synaptic plasticity, as it helps organize microtubules that extend into dendritic spines, the sites of synaptic connections and communication Dysregulation or loss of MAP2 function is associated with neurodegenerative diseases such as Alzheimer's disease and tauopathies, where disrupted microtubule stability leads to impaired neuronal function and neurofibrillary tangles MAP2 also serves as a marker for dendritic structures in neurons and is important for maintaining the organization of the central nervous system during development and in response to injury

Características del producto

category

Proteins and Peptides


origin

Mouse


host

E. coli


immunogen target

Microtubule Associated Protein 2 (MAP2)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 61.2 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Thr1457-Ser1728 Tag: N-terminal His tag and GST tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

MAP2


dry ice

No


availability

Shipped within 5-12 working days.


alias

MAP-2,MAP2A,MAP2B,MAP2C


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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status

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clonality

polyclonal

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