Mouse Melanocortin receptor 4 (MC4R) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for MC4R
proveedor
Abbexareference
abx515711Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Melanocortin receptor 4 (MC4R) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Melanocortin receptor 4 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
MC4R is a G protein-coupled receptor activated by melanocortins such as α-MSH and ACTH, primarily expressed in the hypothalamus. MC4R plays a central role in regulating energy homeostasis, appetite suppression, and body weight. Activation of MC4R stimulates Gs proteins, increasing intracellular cAMP levels and activating downstream pathways to inhibit feeding and promote energy expenditure. Mutations in MC4R are the most common cause of monogenic obesity, resulting in hyperphagia and reduced energy expenditure. In addition to its role in metabolism, MC4R influences glucose homeostasis, cardiovascular function, and sexual behavior. MC4R agonists are being developed as potential therapeutics for obesity and related metabolic disorders, while antagonists are explored for cachexia and anorexia. MC4R’s critical role in appetite regulation and energy balance highlights its significance as a target for treating obesity, metabolic syndrome, and weight-related disorders.
Características del producto
category
ELISA Kits
immunogen target
Melanocortin receptor 4 (MC4R)
reactivity
Mouse
test range
0.312 ng/ml - 20 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
MC4R,BMIQ20
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
MC4R
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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