Mouse Matrix Metalloproteinase 9 (MMP9) Protein

Background

MMPs are secreted by diverse connective tissue and pro-inflammatory cells. Typically, these enzymes exhibit minimal expression under normal physiological circumstances. MMPs assume a pivotal role in various cellular processes, including cell proliferation, migration, differentiation, angiogenesis, apoptosis, and immunity. They share a common domain structure, consisting of three key components. First is the pro-peptide, which requires removal to activate the enzyme. Next, there is the catalytic domain, featuring a cysteine switch, where a cysteine residue interacts with zinc, and the haemopexin-like C-terminal domain is linked to the catalytic domain via a flexible hinge region. MMP-9, alternatively known as 92 kDa type IV collagenase, 92 kDa gelatinase, or gelatinase B (GELB), belongs to the zinc-metalloproteinases within the Matrixin family. In humans, the MMP-9 gene is responsible for encoding this enzyme. MMP-9's substrates include gelatin and collagen types IV and V. This gelatinase, MMP-9, has been associated with various medical conditions, including the development of atherosclerosis, chronic obstructive pulmonary disease (COPD), tumor formation, metastasis, and wound repair

Características del producto

origin

Mouse

host

Yeast

immunogen target

Matrix Metalloproteinase 9 (MMP9)

host

Yeast

conjugation

Unconjugated

form

Lyophilized

tested applications

WB, SDS-PAGE

size 1

50 µg

size 2

100 µg

size 3

200 µg

size 4

1 mg

size 5

5 mg

expression

Recombinant

purity

> 95%

buffer

Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 5% Trehalose and Proclin-300.

storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.

or code

MMP9

dry ice

availability

Shipped within 5-7 working days.

alias

GELB,CLG4B,MMP-9,MANDP2,92 kDa type IV collagenase, Gelatinase B

uniprot id

https://www.uniprot.org/uniprotkb/P41245

note

This product is for research use only. <p></p> Not for human consumption, cosmetic, therapeutic or diagnostic use.

Quizá le pueda interesar

Matrix Metalloproteinase-9 (MMP9) Antibody

proveedor

Abbexa

reference

abx001707

Tested Applications

reactivity

Human, Mouse

status

RUO

clonality

Polyclonal

MMP9 Antibody is a Rabbit Polyclonal antibody against MMP9. Proteins of the matrix metalloproteinase (MMP) family are in...

175€ (20 µl)

Human Matrix Metalloproteinase 9 (MMP9) ELISA Kit

proveedor

Abbexa

reference

abx152365

Tested Applications

ELISA

reactivity

Human

status

RUO

Human Matrix Metalloproteinase 9 (MMP9) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human MMP...

525€ (96 tests)