Mouse Lysine-specific demethylase PHF2 (PHF2) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for PHF2
proveedor
Abbexareference
abx538659Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Lysine-specific demethylase PHF2 (PHF2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Lysine-specific demethylase PHF2 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
PHF2 is a histone demethylase that specifically targets H3K9me2 to activate transcription by removing repressive methyl marks on histones. It serves as a transcriptional co-activator that regulates gene expression in response to metabolic and cellular stress signals. PHF2 is recruited to gene promoters through interactions with transcription factors and chromatin-associated proteins, promoting the activation of genes involved in lipid metabolism, gluconeogenesis, and inflammatory responses. It is expressed in metabolic tissues such as the liver, skeletal muscle, and adipose tissue, where it plays a role in energy homeostasis and inflammation control. Dysregulation of PHF2 is associated with metabolic diseases, including obesity, diabetes, and cancer, where its role in histone demethylation is disrupted. Knockdown studies reveal decreased transcriptional activation, impaired lipid metabolism, and abnormal inflammatory responses, highlighting its role in epigenetic regulation, metabolism, and cellular stress adaptation.
Características del producto
category
ELISA Kits
immunogen target
Lysine-specific demethylase PHF2 (PHF2)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
CENP-35,GRC5, JHDM1E, KDM7C
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
PHF2
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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