Mouse Lymphocyte Antigen 9 (LY9) Protein
507€ (50 µg)
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935106861
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name
Mouse Lymphocyte Antigen 9 (LY9) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx691897
tested applications
SDS-PAGE
Description
Mouse CD229 Protein is a recombinant protein from Mouse produced in HEK293 Cells. A DNA sequence encoding the extracellular domain of mouse Ly9 (NP_032560.2) (Met 1-Arg 453) was expressed, with a polyhistidine tag at the C-terminus.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | CD229 |
| Host | HEK293 cells |
| Origin | Mouse |
| Observed MW | Molecular Weight: 46.5 kDa Sequence Fragment: Met1-Arg453 Tag: C-terminal His tag Validity: The validity for this protein is 12 months. |
| Expression | Recombinant |
| Purity | > 85% (SDS-PAGE) |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | |
| Tested Applications | SDS-PAGE |
| Buffer | Lyophilized from sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | NP_032560.2 |
| Alias | T-lymphocyte surface antigen Ly-9,hly, mLY9,CD229,SLAMF3,Cell surface molecule Ly-9,SLAM family member 3 |
| Background | Protein LY9 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Lymphocyte antigen 9 (LY9), also known as SLAMF3 (Signaling Lymphocytic Activation Molecule Family Member 3), is a transmembrane glycoprotein and member of the immunoglobulin (Ig) superfamily. This molecule is part of the broader SLAM family, a set of proteins primarily expressed on immune cells. LY9, like other SLAM family members, plays a key role in immune cell signaling, cell-to-cell interactions, and immunoregulation, specifically in adaptive immunity. This protein is highly expressed on lymphocytes, particularly T cells and natural killer (NK) cells, and it is involved in mediating various immune responses by interacting with other immune cells. LY9 participates in homotypic interactions, meaning it binds to another LY9 molecule on adjacent cells, facilitating immune cell communication and signaling. Its expression is primarily associated with lymphoid tissues, but it is also present on other immune cells, where it regulates responses by activating intracellular signaling cascades. Studies show that LY9 contributes to immune regulation by affecting processes such as cytokine secretion, cytotoxicity, and immune cell differentiation. Given its involvement in immune signaling, LY9 is being investigated as a therapeutic target in conditions where immune regulation is disrupted, including autoimmune diseases, cancers, and immunodeficiencies.
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