Human Lymphocyte Antigen 9 (LY9) Protein

Product specifications

Proteins and Peptides

Lymphocyte Antigen 9 (LY9)

E. coli

Human

Unconjugated

Molecular Weight: Calculated MW: 25.6 kDa
Concentration: Prior to lyophilization: 200 µg/ml
Sequence Fragment: Val2-Thr212
Tag: N-terminal His tag

Recombinant

> 95%

1 mg

5 mg

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.

WB, SDS-PAGE

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.

Shipped within 1-2 months.

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.

No

Q9HBG7

T-lymphocyte surface antigen Ly-9,hly, mLY9,CD229,SLAMF3,Cell surface molecule Ly-9,SLAM family member 3

Protein LY9

RUO

This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Lymphocyte antigen 9 (LY9), also known as SLAMF3 (Signaling Lymphocytic Activation Molecule Family Member 3), is a transmembrane glycoprotein and member of the immunoglobulin (Ig) superfamily. This molecule is part of the broader SLAM family, a set of proteins primarily expressed on immune cells. LY9, like other SLAM family members, plays a key role in immune cell signaling, cell-to-cell interactions, and immunoregulation, specifically in adaptive immunity. This protein is highly expressed on lymphocytes, particularly T cells and natural killer (NK) cells, and it is involved in mediating various immune responses by interacting with other immune cells. LY9 participates in homotypic interactions, meaning it binds to another LY9 molecule on adjacent cells, facilitating immune cell communication and signaling. Its expression is primarily associated with lymphoid tissues, but it is also present on other immune cells, where it regulates responses by activating intracellular signaling cascades. Studies show that LY9 contributes to immune regulation by affecting processes such as cytokine secretion, cytotoxicity, and immune cell differentiation. Given its involvement in immune signaling, LY9 is being investigated as a therapeutic target in conditions where immune regulation is disrupted, including autoimmune diseases, cancers, and immunodeficiencies.

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