Mouse Lpar3 (Lysophosphatidic acid receptor 3) ELISA Kit
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name
Mouse Lpar3 (Lysophosphatidic acid receptor 3) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EM0486
tested applications
ELISA
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | 4 hours |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 0.156-10ng/ml |
| Sensitivity | 0.094ng/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| UniProt ID | Q9EQ31 |
| Alias | LPAR3,EDG7,Edg-7,GPCR,HOFNH30,LP-A3,LPA3,LPA receptor 3,endothelial differentiation gene 7,lysophosphatidic acid G-protein-coupled receptor 7 |
| Background | Elisa kits for Lpar3 |
| Status | RUO |
LPAR3 is a G protein-coupled receptor for lysophosphatidic acid (LPA), widely expressed in reproductive tissues, cardiovascular cells, and epithelial tissues. It signals through Gq, Gi, and G12/13 proteins, activating downstream pathways such as phospholipase C (PLC), MAPK, and Rho/ROCK. LPAR3 plays a crucial role in embryonic development, particularly in implantation, embryo spacing, and uterine function. Dysregulation of LPAR3 impairs fertility and embryonic viability, as evidenced in animal models. In cancer, LPAR3 promotes tumor progression, angiogenesis, and metastasis, particularly in breast, ovarian, and colorectal cancers. LPAR3 activation enhances cancer cell migration and survival, making it a key contributor to cancer aggressiveness. In the cardiovascular system, LPAR3 regulates vascular tone and endothelial cell function, contributing to blood vessel integrity. Dysregulated LPAR3 signaling has been implicated in chronic inflammation, atherosclerosis, and fibrotic diseases. Therapeutic strategies targeting LPAR3 aim to modulate its roles in reproduction, cancer, and inflammatory diseases.
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Mouse Lpar3 (Lysophosphatidic acid receptor 3) ELISA Kit
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