Mouse Low Density Lipoprotein Receptor Related Protein 1 (LRP1) CLIA Kit

Este producto es parte de LRP1 - LDL receptor related protein 1
Mouse Low Density Lipoprotein Receptor Related Protein 1 (LRP1) CLIA Kit
845€ (96 tests)

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Name
Mouse Low Density Lipoprotein Receptor Related Protein 1 (LRP1) CLIA Kit
Category
CLIA Kits
Provider
Abbexa
Reference
abx492317
Tested Applications
CLIA

Description

Mouse Low Density Lipoprotein Receptor Related Protein 1 (LRP1) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Serum, plasma and other biological fluids.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
CLIA Kits
Immunogen Target
Low Density Lipoprotein Receptor Related Protein 1 (LRP1)
Reactivity
Mouse
Detection Method
Chemiluminescent
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
1.56 ng/ml - 100 ng/ml
Sensitivity
< 0.63 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Standard: Lyophilized
Tested Applications
CLIA
Sample Type
Serum, plasma and other biological fluids.
Availability
Shipped within 5-20 working days.
Storage
Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
Alias
Prolow-density lipoprotein receptor-related protein 1,Alpha-2-macroglobulin receptor,APR,KPA,LRP,A2MR,CD91; DDH3,APOER,LRP1A,TGFBR5,IGFBP3R,IGFBP-3R,IGFBP3R1,LRP-1,Apolipoprotein E receptor
Background
CLIA Kits LRP1
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES.  The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.  Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Background

Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) is a multifunctional cell surface receptor with diverse roles in cellular processes, including endocytosis, lipid transport, signal transduction, and the regulation of inflammation. Part of the low-density lipoprotein (LDL) receptor family, LRP1 has high sequence homology with the LDL receptor but a much broader set of ligands, facilitating interactions with various proteins, such as apolipoprotein E (ApoE), tissue plasminogen activator (tPA), and matrix metalloproteinases. LRP1 is highly expressed in the liver, brain, and adipose tissues, where it plays crucial roles in metabolism, neuroprotection, and vascular health. In neurons, LRP1 mediates neuroprotective processes and is implicated in the clearance of amyloid-beta, a key protein in Alzheimer’s disease pathology. In addition to metabolic and neural roles, LRP1 impacts cellular migration and adhesion, contributing to processes related to tissue injury repair, cancer metastasis, and inflammatory diseases. Its function and widespread expression make LRP1 a focal point in therapeutic research for conditions including neurodegenerative diseases, atherosclerosis, and certain cancers.

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